However, these are not elements of the AgeEtranger series. They have no other choice – the game must set itself apart from classic scenes revisited to face internal competition. On the other hand, they introduce a lot of completely new elements. On the one hand, it seems that they are trying to preserve the essential characteristics of the cycle in order to reach people who have spent half their lives with it. So, the creators of Part IV have no easy task. The remasters, on the other hand, were aimed primarily at fans of the series. Descargar age of empires ii gratis series#Along with the updated versions, we got the last entirely new installment in the series in 2005. Age of Empires 4 torrent, despite the already familiar historical period of the Middle Ages, looks more like a fresh start. But that’s the norm for any popular game franchise, after all. I suspect, however, that many die-hard fans of the show, with their own ideas of what the show looks like, will turn their heads. Age of Empires gamesThey can seem chaotic during clashes The creators justified the decision on this style and not another by the transparency of the game. It’s hard to see in still screenshots, but it’s evident when you watch the game in action. As for the “fours,” however, it seemed to me that there were two graphic styles that didn’t like each other very much. The Age series has always been characterized by rich colors. Added to this is the effect of distorted proportions: units look really big next to buildings.ĭon’t get me wrong though – I’m the last person to think that reduced saturation makes the game more mature and prettier. Slightly angular and very colorful unit models stand out against their background. The grounds and surroundings are extremely detailed and beautiful. In the case of’ Age of Empires 4, I felt like I was watching a kid from previous games and… the Settlers. Descargar age of empires ii gratis Pc#Age of Empires 4 – minimum PC hardware requirements.Age of Empires 4 – Recommended PC Hardware Requirements.I also saw a scout on horseback hunting a boar,.The high civilization asymmetry of a few.Of the eight nations that will appear in the game.Changes in mechanics and new attractions.Age of Empires gamesThey can seem chaotic during clashes.I myself have never attached much importance to the appearance of any given game series, but I do realize that the Age series has its own unique atmosphere, which also owes its audiovisual setting. Descargar age of empires ii gratis download#What pc download games is shown to us is the unfinished version. Honestly, the first thought that came to my mind after seeing the game in Age of Empires 4 pc was, “It doesn’t look like Age of Empires. The question arises: is there a place for another Age- game branding game in the Middle Ages? Without a doubt, however, Age of Empires 2 Definitive Edition stands out from the background of these productions. Let’s not forget the spin-off of this series, Age of Mythology, which is also available on Steam. There are currently four Age of Empires games on the market that are doing pretty well, although real-time strategy games are long overdue. Relic Entertainment, known from series like Company of Heroes or Warhammer 40,000: Dawn of War, is at the origin of its creation. Age of Empires 4 free download is the fourth full-fledged installment of the famous real-time strategy series, set in the Middle Ages.
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Further topics will highlight the application of NGS towards routine practice, including variant detection, whole-genome sequencing (WGS), whole-exome sequencing (WES) and multi-gene panels. This chapter encompasses revised concepts, applications, advances, limitations and the history of technological advances until the emergence of NGS technique in the era of precision medicine, starting with a brief history of DNA sequencing followed by a comprehensive description of most used NGS platforms, sequencing chemistries methodology and general workflows. Thanks to second-generation sequencing technologies, it has become easier to sequence the expressed genes (‘transcriptomes’), known exons (‘exomes’) and complete genomes of patient’s samples. One of the major near-term medical impact of the NGS revolution will be the elucidation of mechanisms of human pathogenesis, leading to improvements in the diagnosis and the selection of treatment and prevention. A great challenge will be the interpretation of this great number of data and its translation for the medical application. Among the available NGS applications, one of them will be the resequencing of the human genome and the better genetic understanding of various human diseases. The NGS allows producing millions of data with a smaller investment. The emergence of NGS has changed the way clinical research, basic and applied science are done. NGS allows identifying biomarkers for early diagnosis as well as for personalized treatments. In recent times, Sanger sequencing, referred to as a ‘first-generation’ sequencing method, has partly been replaced by ‘next-generation’ sequencing (NGS) methods. There is a great deal of investment nowadays in prevention using these new technologies, as opposed to old medicine based on treatment since the disease was already evident or irreversible. Precision medicine redefines the way traditional medicine is practised. Īs a result of the genome project, many molecular tools have been developed and allow medical and scientific groups to improve patient management based on a better understanding of disease biology, providing a more specific and accurate prevention and treatment of diseases. It is estimated that about 75 billion US dollars per year (30% of health care expenditure) are destined for unnecessary or ineffective treatments in the USA. Statistics indicated that traditional clinical practices sometimes lead to poor health outcomes and also a waste of medical resources. The molecular knowledge has contributed strongly to the advancement of precision medicine, providing specific strategies for target therapies and diagnosis of patients with cancer, Mendelian diseases and others. Precision medicine is a new way of practising medicine, which has been gaining strength in recent years, is based on the individual characteristics of each patient (genetic, environmental, behavioural) to optimize and customize strategies for prevention, detection and therapy. A centralized chapter describing the main NGS aspects in the clinic could help beginners, scientists, researchers and health care professionals, as they will be responsible for translating genomic data into genomic medicine. The potential use of NGS in precision medicine is vast and a better knowledge of this technique is necessary for an efficacious implementation in the clinical workplace. Further topics will highlight the application of NGS towards routine practice, including variant detection, whole-exome sequencing (WES), whole-genome sequencing (WGS), custom panels (multi-gene), RNA-seq and epigenetic. This chapter attempts to review the main features of NGS technique (concepts, data analysis, applications, advances and challenges), starting with a brief history of DNA sequencing followed by a comprehensive description of most used NGS platforms. The traditional medicine model of diagnosis has changed to one precision medicine model, leading to a more accurate diagnosis of human diseases and allowing the selection of molecular target drugs for individual treatment. The relatively fast emergence and success of NGS in research revolutionized the field of genomics and medical diagnosis. Next-generation sequencing (NGS) technologies represented the next step in the evolution of DNA sequencing, through the generation of thousands to millions of DNA sequences in a short time. The Who took the stage earlier Sunday and rocked through hits from their discography for just over two hours. "I'm going to send out all of my most heartfelt love and support to all those young people on the campuses of the universities of California who are standing up for their brothers and sisters in Palestine and supporting the BDS movement," he said, "in the hope that we may encourage the government of Israel to end the occupation."īefore closing with "Vera" and "Comfortably Numb," Waters told the audience, "It's been a huge honor and a huge pleasure to be here to play for you tonight." The former Pink Floyd frontman waited until near the end of his performance to voice his support for the Palestinian-led BDS movement, which calls for boycotts and sanctions against the Israeli government. His set also included "Time," ''Money," ''Wish You Were Here" and "Dark Side of the Moon." He dedicated the song to all victims of war and violence. "Working with these men has been one of the most rewarding things I've ever done in my life," Waters said. Waters told the crowd that he's been working with wounded warriors in Washington, D.C., and brought a young American veteran who lost his legs onstage to play lead guitar with the band on "Shine on You Crazy Diamond." "I cannot believe I still have to protest this (expletive)," another said. As he performed "Us and Them," the big screen showed pictures of protest signs. While other Desert Trip performers mentioned the presidential election, Waters was the only one who brought up the Black Lives Matter movement in front of the overwhelmingly white audience. Waters followed up with "Another Brick in the Wall (Part II)," during which 15 school-age children came onstage wearing T-shirts that read, "Derriba el muro" - Spanish for "Take down the wall." Roger Waters performs on day 3 of the 2016 Desert Trip music festival at Empire Polo Field on 9 Oct. Having a strong financial bedrock will make everything easier to build upon, and having funds is essential to expanding. While you might see the high amount of worker buildings that produce “things” don’t neglect office buildings. If you expend your initial collection of matter, you’ll not have sufficient resources to build the matter mine, and eventually zero out on matter which means game over. Without this growth, your finances will stagnate, and you’ll be left in a situation where you deplete on resources that you can’t rebuild.Īn example of this is to make sure you build a matter mine right away once you get your first batch of people. Keeping production moving forward is important – growth of the population, available jobs, and resources is key. Blue medium spaces on the edges not facing another cliff are ideal spots for landing platforms, and the orange medium spaces near lakes are the only spots where you can put fishing ports. Placing something here means that you’ll eventually have to tear it down if you want to connect the two with a bridge. For instance, on the blue medium spaces that are on the side of a cliff near another cliff, you can build a bridge to the other side. The results will be more fruitful.įor spaces with special structure placements, avoid placing generic buildings there. For instance, having a cliff with 80% windiness and 20% sunshine, means you should not build solar panels, and only build wind turbines. In a similar vein, this helps you with knowing what to build. What this reflects is the ability to produce off this cliff – if you start in a location with low Sunshine and Windiness, you’ll spend a lot of resources and space building the relevant power systems to keep it powered. What is important is that you have a fairly high ground water, and at least Sunshine or Windiness in high quantities. You’ll notice that no information is available immediately on soil quality, matter deposits, or uranium deposits. Scout around the map and look at the information on each cliff. Each plot type allows for different buildings that are only available for that plot size, so build carefully. The special blocks are always on the medium sized spaces, are colored either blue or orange, and denote something special can be built there. Small and large are both squares, while medium and extra-large are rectangles. There are 5 plot types: small medium large extra-large special. Below is just a list of items to think about while getting started, and some lessons learned from a few early games that brought me to a screeching halt.įollow the mission / tutorial! It will get your first colony up and running smartly. So the UI seems simple at first, but it’s a lot to decompress. #Drone station cliff empire full#Unemployment benefits is a vital negative which indicates that you have population not working and must pay them from your funds every time the stopwatch performs a full cycle.Loans to this city are shown in the center indicating the remaining loan to be repaid.Your current funds are indicated at the left.This includes Soil Fertility, Matter deposits, Groundwater, Sunshine, Windiness, Fish, and Uranium deposits. Expanding this by clicking the will show more detailed information.In the game, you’ll spawn with 2-3 cliffs available, each with its own name, resources, and build area. This shows the name of the current cliff/city that you are hovering over.In this case, this would be at a 45-degree angle vertically, with the camera being centered on the corner of the building grid and complete removal of depth of field. People familiar with Sim City and some other games may be familiar with this term, but in short, it locks the camera into a mode where all 3d objects appear to be perfect 2d representations of the item. The hourglass button is the game speed controller.Completion of these goals results in a financial reward.Ģ: Game Speed and Cursor Illumination Buttons.This section denotes the next suggested action and shows the way forward through the game. Supports main AV formats & video codecs (avi, mjpeg, mov, mp4, mpeg…).Import your own images and logos onto the grid (jpeg, png & bmp).Import your own video & audio samples onto the grid (100 seconds max).Overlays: includes 13 transparent background video samples.Generators: includes 48 real-time generated, BPM -synced and audio-reactive video samples.36 royalty-free professional audio samples. #REMIXVIDEO WITH APC40 720P#144 royalty-free professional video samples (available in 404p, 720p & 1080p).Audio Live Input: analysis of BPM, frequencies and waveform of external sources.Auto-Pilot: automatically plays a sequence of pads.Live BPM control: time stretch included.Built-in mixer: audio & video faders, bi-filter knobs, EQs, mute & solo buttons.Video sample editor: hue, contrast, brightness, saturation, chroma key, position & scale.Audio sample editor: quantize, gain, mute audio.Includes 144 video samples (in 404p, 720p & 1080p) & 36 synced HQ audio samples.Import video & audio samples: all main A/V formats & video codecs are supported.Ableton Link: play in sync on several devices running Link-enabled apps.Tweak visuals instantly with video FX, mixing modes and real-time editing.Play fully-synced video & audio samples on a grid of pads.Remixvideo is the weapon of choice for creative video mixing, with a slick grid interface that makes DJs/producers instantly feel at home. Having pioneered VJing with Cross, Mixvibes now brings you an accessible way to step into the world of video mixing. Enhance your live shows with Remixvideo, the intuitive video sampler. Studio was built on the industry-standard Unity gaming engine and is designed to integrate with the BrickLink Marketplace. #Lego digital designer render software#In 2014, then-independent BrickLink created the BrickLink Studio software as a free virtual LEGO building tool. The talented team behind Studio see this clearly and continue relentlessly to further innovate and improve the Studio experience”. For digital building to be not only a nice feature for some, but a meaningful part of many people’s LEGO building experience, it must be an integrated and useful part of both the design, the building and the sharing experience. “When the LEGO Group acquired BrickLink,” Askildsen said, “one of the things that impressed and inspired us was their purposeful development of the Studio software. Tormod Askildsen, head of AFOL Engagement for the LEGO Group, has been intrigued by digital building since using LDD to bring alternate model instructions for the LEGO Factory Hobby Train set to market in 2007. They have truly inspired a generation of digital LEGO creators.” I am so proud of the team behind LDD and the greater virtual building community. They took ownership and created the most amazing virtual LEGO models and have grown the virtual building ecosystem. Builders-enthusiasts and professionals alike-have used LDD in wonderful and unexpected ways. “I am so impressed with how the community of creators has evolved. “Our initial vision for LEGO Digital Designer back in 2002 was to make building on a computer accessible and fun for children – to play with and share their creations online.” said Ronny Scherer, producer of the first-generation LEGO Digital Designer. Now after almost twenty years since its conception and eighteen years in distribution, LEGO Digital Designer will retire and pass the mantle to BrickLink Studio as the officially supported and maintained 3D building application. It has played a prominent role in various offerings, from LEGO Factory, LEGO Design ByME, LEGO video games and movies. LDD pioneered real-time rendering of LEGO bricks, virtual brick connectivity, and the compact LEGO Exchange file format (LXF) which made LEGO models built in LDD light and portable. LEGO Digital Designer was released in 2004 as the LEGO Group’s 3D building tool. #Lego digital designer render download#While downloaded versions of the LDD application will continue to work, people are encouraged to download BrickLink Studio, import their LDD files, and use Studio for 3D LEGO building files, and use Studio for 3D LEGO building. The LEGO Digital Designer (LDD) website will close on January 31st, after which time LDD will no longer be available for download. Today, the LEGO Group announces that BrickLink Studio will replace LEGO Digital Designer as the official virtual LEGO building software going forward. It simplifies things making your work fast and easy. This machine is flexible in that you can use it on both Mac and PC to make your professional designs. Below is a detailed description of its features. The easy cut has very many features, something that makes it one of the best tools for crafters. #EASY CUT STUDIO PRO FULL#The easy-cut studio software includes a text layout, image tracing features, and full graphic design. It can weld print cuts and shapes What’s Included?.Uses any font on your computer or any SVG image.Can be used by any level user and you can use any of the installed fonts.Some users complained that the controls of its functions are disorganized.It lets you create and make changes to your designs.The best thing about it is that even entry-level users can use it. It is also great for rhinestone lovers as it allows them to create their rhinestone templates. This is because it has a wide range of drawing and editing tools. The easy-cut studio is perfect for crafters who are planning to create various types of designs. Conclusion Who Is Easy Cut Studio Designed for?.The software is compatible with both Mac and Windows. #EASY CUT STUDIO PRO PRO#Welding layers of letters and shapes to overlap one another ĮasySignCut Pro – Vinyl plotter software supports a wide range of vinyl cutters, including Craftwell eCraft, Roland, GCC, Saga, SignKey, Summa, BossKut, Seiki, BlackCat, USCutter, Liyu, Redsail, Creation PCut, TENETH, Foison, GoldCut, KNK, Ioline, PixMax, Refine, Secabo, Cougar/Lynx, Pazzles Inspiration, Silhouette SD/CAMEO/Portrait, VicSign, SilverBullet and Vinyl Express machines.Cut end action to go back to origin, advance a specified amount, or do nothing.Applying various effects to the design (including: 3D Rotate, Bulge, Canned, Lattice and Shadow Layer).Weeding options to easily add weeding boxes and lines.Extended cutting length to cut longer than 72 inches.In addition, the software provides useful features such as: This plotter software has a built-in library which features hundreds of preset shapes and available fonts for design needs. Users can also create their own images with the suite of powerful drawing tools that comes with the software. There is also the feature of Image tracing utility which allows automatic conversion of all kinds of images into cuttable vector graphics. Users can import vector graphics in various formats (such as SVG, PDF), then edit or cut the graphics. It provides users with the ability to work with installed TrueType fonts and draw shapes for cutting. #EASY CUT STUDIO PRO REGISTRATION#The state-of-the-art software offers a vast amount of advanced functions and tools dedicated to designing and laying out all types of vinyl lettering, signs, decals, posters and graphic artwork to be cut out using a Vinyl Cutter.ĮasySignCut Pro Edition enables users to contour cut around vector artwork and print from EasySignCut using Registration Mark and load the printed sheet to the cutter, followed by calibration of ther cutter in simple steps for contour cutting. The Pro version is designed for businesses that use the larger vinyl plotters.ĮasySignCut Professional is a full-featured sign design and vinyl cutting software specifically created to be compatible with vinyl cutters (plotters). It offers users an easy and efficient way to making signs, lettering, logos, stickers and decals using a vinyl cutter or vinyl plotter. Eas圜ut Studio has announced its newly-developed professional version of vinyl plotter software - EasySignCut Pro, the software includes a host of advanced features plus accurate contour cutting capability.
With their soft ear buds these are comfortable enough to wear all day. SKULLCANDY EFFORTLESS SOUND PLUSIn addition they are water and sweat resistant and lightweight, making them rugged for various activities, plus they come in a wide range of combination colours. These balance style with practicality by fitting snugly yet comfortably over the contours of your ears, perfect for those active consumers. These phones have super soft silicone earbuds for listening to your favourite music comfortably and call, track and volume controls. They also feature a long life rechargeable battery that can last up to seven hours, so you can stay on the go outdoors for hours on end. These make great headphones for when you're active as the cords run behind your neck, keeping the out of the way of your arms as you move around. The Smokin' Buds 2 wireless headphones are lightweight with a behind the neck style. Noise cancellation makes these headphones the perfect choice for when you are traveling by blocking out background noise such as on a train or car journey. This way you can hear your music, podcasts and audiobooks with optimal clarity. Many of Skullcandy's headphones feature noise cancelling abilities, which are built to block out external noise from coming through your headphones and affecting the sound quality of your audio. Plus, Skullcandy have worked with acoustic engineers to produce exceptional, world class sound quality. SKULLCANDY EFFORTLESS SOUND PORTABLESkullcandy headphones make a great travelling device by being portable and made from durable materials, limiting the results of bumps and knocks. Skullcandy headphones are resistance to moisture, water and sweat, making these headphones rugged and durable for sports activities such as running. Skullcandy boast carefully balanced new technological innovations with unique designs that catch the eye, in a great range of headphones to suit different styles and scenarios. The feature is intuitive and easy to set up via the Tile mobile app.Known for producing some of the leading headphones and audio output devices on the market, Skullcandy headphones will not disappoint. I like that the functionality is embedded in each earbud, so you can track them individually. Oddly they aren’t available in as many colors - you can only order them in black or gray (at least for now).Ī built-in Tile tracker sets the Indy Fuel earbuds apart from all similarly priced competitors. Save for the slight change in the design of the stability ear inserts, the Fuel wireless earbuds look just like the Skullcandy Indy that debuted last year. Managing the audio playback, the volume, and taking calls was easy, but changing equalizer settings and switching ambient mode on and off required quite a bit of practice. However, I was less impressed by the earbuds’ finicky touch controls. The retail package contains several sets of tips and stability ear gels for finding a perfect fit. Would you buy this Yes 3 No 0 Price 129.95 (AUD) Skullcandy dont sound like a brand you would associate with high end audio, so the performance of their Ti headphones came as a bit of a surprise. Sadly, the absence of Qualcomm aptX support, which would have been a wonderful addition, was a negative for me. If you are a fan of flamboyant music accessories and want some headphones with above average sound quality, the Skullcandy Ti may be for you. SKULLCANDY EFFORTLESS SOUND BLUETOOTHThey are wireless headphones that employ Bluetooth 5, which supports the SBC and AAC codecs, for connectivity. Having stems like the Apple AirPods means that the earbuds sit securely in the ear without protruding unnecessarily. The Skullcand圜rusherEvoHeadphones offer a staggering 20,000Hz frequency range and are powered by 40mm dynamic speakers. I was pleasantly surprised how comfortable the Indy Fuel earbuds felt in my ears. The buds’ performance during calls was solid, but not the best I’ve experienced in this price range. It allows them to maintain a reliable, latency-free connection. Unlike last year’s Push earbuds, the Skullcandy Indy Fuel are equipped with Bluetooth 5.0 connectivity. SKULLCANDY EFFORTLESS SOUND MOVIEThe movie setting, curiously, balances the bass and the treble surprisingly well. The music setting brings the powerful bass experience I described above, while the podcast preset eliminates it almost completely. The earbuds have a trio of equalizer presets (music, movie, and podcast), accessible via their built-in touch controls. The change in vendors will bring many benefits to their patients including increased security, improved continuity of care, and more access to providers and medical documents. SUBLER EYECARE SOFTWAREPractices include measurement of client's eyes, face, and distance between their pupils, preparation of work orders for ophthalmic laboratory technicians.GREENVILLE, January 2018 – Family Health Services will be upgrading their electronic medical record (EMR) software in January 2018. Medical tests, procedures and therapies provided by Opticianry Opticianry practices include farsightedness and nearsightedness. Significant diseases and conditions treated at SUBLER EYECARE PROFESSIONALThe professional practice of filling prescriptions for ophthalmic lenses, dispensing eyeglasses, and fitting contact lenses. Measurement of client's eyes, face, and distance between their pupils determination of appropriate eyewear for sports needs, work environment, or style preference preparation of work orders for ophthalmic laboratory technicians adjustment or repair of broken eyeglass frames education of client on eyewear care and cleaning. With healthcare providers who have special training and skill in designing, verifying and fitting eyeglass lenses and frames, contact lenses, and other devices to correct eyesight by fulfilling prescriptions supplied by ophthalmologists or optometrists. Vision One is an Opticianry practice in Fort Mitchell, KY Optometrists are eye health care professionals state-licensed to diagnose and treat diseases and disorders of the eye and visual system. Some optometrists complete an optional residency in a specific area of practice. An optometrist has completed pre-professional undergraduate education in a college or university and four years of professional education at a college of optometry, leading to the doctor of optometry (O.D.) degree. Optometrists examine, diagnose, treat, and manage diseases, injuries, and disorders of the visual system, the eye, and associated structures as well as identify related systemic conditions affecting the eye. Practices include visual acuity test, color blindness test, cover test, eye movement test, depth perception test, retinoscopy, refraction test, as well as autorefractor and abberrometer prescription estimate.ĭoctors of optometry (ODs) are the primary health care professionals for the eye. Medical tests, procedures and therapies provided by Optometry Optometry practices include conjunctivitis, diabetic eye disease, glaucoma, and macular degeneration. The practice or profession of examining the eyes for visual defects and prescribing corrective lenses. With healthcare providers who have special training and skill in examining eyes for both vision and health problems, and correcting refractive errors by prescribing eyeglasses and contact lenses, as well as providing low vision care and vision therapy.Įye exams to detect any vision problems or diseases requires testing visual acuity, depth, and color perception, as well as the ability to focus and coordinate the eyes. Vision One is an Optometry practice in Fort Mitchell, KY The words printed beneath the statue state, “My name is Ozymandias, King of Kings: Look on my works, ye mighty, and despair” (Shelley 10-11). Shelley, similar to Lazarus, uses the element of personification to characterize the statue. The subject is similar to that of “The New Colossus,” because it is described as a powerful statue. “Ozymandias” is a poem about a decayed statue. The tone of the poem is idealistic because Lazarus describes a statue that represents a righteous and perfect America. This golden door is representative of an ideal America where good opportunities are plentiful and easily accessible. The statue itself is personified with the dialogue, “Send these, the homeless, tempest-tost to me, I lift my lamp beside the golden door” (13-14). By titling the poem as “The New Colossus,” Lazarus is comparing this statue of freedom to a statue of light and hope. The analogy to the Greek sun god, Colossus, relates the statue to a famous figure known for radiance. She describes it as “Mother of Exiles” (6), portraying the statue as a maternal, loving, and nurturing figure that welcomes those who have come to her from places of struggle. Lazarus herself was part of a family who immigrated to the United States, which explains why she would have a positive and idealistic opinion of the statue. The Statue of Liberty is now recognized as a symbol of freedom and refuge for people of all nationalities and homelands. This method of personification is effective to get across Lazarus’s own opinion about the statue, because the dialogue explains how maternal and welcoming the statue is and what she represents. The statue’s words are “cried…with silent lips” (9-10). Lazarus writes six of the fourteen lines of the poem as personified dialogue of the statue. The most prominent way that Lady Liberty is personified is through the use of dialogue. In her poem, Lazarus uses personification as a figurative element to paint a literary picture of the statue. This statue is a powerful symbol of freedom and welcome, and Lazarus describes it as “a mighty woman” (4). In “The New Colossus,” Lazarus is describing the Statue of Liberty. |
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